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To melt a covalent network solid like diamond (carbon) or quartz (silicon dioxide), you must break these powerful covalent bonds

Subsequent review of the raw data revealed that the improvement and recovery rates were not significantly different from the control participants

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protein misfolding, mislocalization of TDP-43 to the cytoplasm, ER stress, inhibition of ER-Golgi transport, and apoptosis, in neuronal cells expressing pathological forms of TDP-43 or SOD1 (Parakh et al., 2020)