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In peripheral biomarker studies, AD patients commonly exhibit elevated serum ferritin and reduced levels of soluble transferrin receptor (sTfR), suggesting impaired systemic iron utilization (Chatterjee et al., 2023)

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In summary, when exposed to H 2 O 2 or LPS induction, pretreatment with either 100 M -EC or the UDE containing 100 M -EC demonstrates a neuroprotective effect that is primarily attributed to the provision of the limiting substrate (-EC) and the promotion of GSH synthesis

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