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Liraglutide (also called Saxenda) Semaglutide (also called Wegovy) Tirzepatide (also called Mounjaro) These medications work slightly differently but the most common are known as GLP-1 agonists which function by manipulating the GLP-1 hormone the body naturally releases when you eat food

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Nausea is the most commonly reported early side effect and tends to ease within the first month as the body adjusts

Clinical Note: While no formal pharmacokinetic drug interaction exists between cannabis and semaglutide, high-THC products may counteract the medication's appetite-suppressing effects