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Nat Commun (2018) 9:1680

The symptoms of an alcohol overdose are similar to those of other depressants

GPX4 converts glutathione (GSH) to oxidized glutathione (GSSG) and converts lipid peroxides to the corresponding alcohols, thus preventing the occurrence of Fenton reactions and subsequently inhibiting ROS generation ( A key component of the cellular antioxidant system, System Xc is a type of amino acid anti-transporter that is substantially dispersed in a lipid bilayer and is a very selective cystine uptake system ( consists of two subunits, one is solute carrier family 7 member 11 (SLC7A11) and the other is solute carrier family 3 member 2 (SLC3A2), which enables the import of cystine from the extracellular space

Gas-liquid Chromatography The methyl esters of fatty acids of the different fractions were prepared by direct transesterification 19