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All key secondary endpoints met, including: BICLA response at week 52 Sustained corticosteroid control (week 4052) SRI-6 response and time to first flare Importantly, no new safety signals were observed, and the safety profile was consistent with prior data
L.ListiA.CarusoS.AmodeoV.PassigliaF.BazanV.et al (2017)
Food Chem 223:2530
Conversely, reactive astrocytes produce TNF- and IL-6, further enhancing microglial activation and inflammation [141,142,143,144]