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Geneva: ICH, 2000

Crosley EJ, Elliot MG, Christians JK, Crespi BJ

By supporting telomeres, it may slow cellular aging and offer anti-aging benefits

Cell 176 , 5672 (2019)

The TMD of cytochrome P450 family 51 subfamily A member 1 (CYP51A1) has been demonstrated to be dependent on RNF185 for substrate recognition, 100 in which degrons in both the ER lumen and the TMD are needed, indicating that substrate selection is governed by multiple determinants as part of ERAD fidelity