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Dietary supplements should not be used as a substitute for a varied diet or a healthy lifestyle

[DOI] [PMC free article] [PubMed] [Google Scholar] Bernstein AM, Sun Q, Hu FB, Stampfer MJ, Manson JE, Willett WC

Nattokinase is an enzyme derived from natto, which is a Japanese fermented soybean paste that is also, incidentally, very high in vitamin K2, which helps you protect against calcium deposits that weaken the plaque and make it more likely to rupture

doi: 10.1016/j.talanta.2011.05.036 79 ZhangGZhangJDeHoogRJPennathurSAndertonCRVenkatachalamMAet al

As of early 2026, cagrilintide is not FDA approved as a standalone medication