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Once activated, they express -smooth muscle actin (-SMA) and synthesize collagen, as well as other extracellular matrix proteins, such as fibronectin [11]

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Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1