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MRP3 can transport some bile acids, specifically conjugated forms, out of hepatocytes into the blood, providing an alternative route for excretion when canalicular transport via MRP2 or BSEP is impaired

However, these coding algorithms have been validated and commonly used in research [77, 78], and any misclassification is likely to be non-differential, which would bias results toward the null rather than create spurious associations

State of the art and perspectives of gene therapy in heart failure

Frster, and H

Clinical protocols typically recommend subcutaneous injection of 250-500 mcg daily, administered consistently for 3-4 months to allow complete spermatogenesis cycles