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-Only 1 in 10 trial participants was over 65 -Risk of drug interactions (seniors take 5 Rxs on avg) -Many have multiple chronic conditions -Loss of lean muscle mass ...but NO clearrisk of falls/fractures GLP-1s in Seniors: Risks and Considerations GLP-1s & SENIORS: a risky experiment

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Similarly, an ML-driven multi-omics integration approach, combining transcriptomic and genomic variation data, has effectively pinpointed highly multidrug-adapted traits within the Cryptococcus gattii species complex (Fan et al., 2024)