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The Epidemiology of T2D The alarming present and forecasted global prevalence of T2D has stressed the need to evaluate novel treatment strategies that could complement lifestyle modifications and conventional pharmacological treatments [10,11,12]

Also, several pathogenic mechanisms linked to ALS involve redox-sensitive proteins, including protein disulfide isomerase (PDI), thioredoxin, and glutathione (GSH), and recent evidence highlights their importance in neurodegeneration

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