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These included signs of distress such as 20% body weight loss, ruffled or matted fur, labored breathing, hunched posture, impaired movement or feeding, lack of response to stimuli, or neurological symptoms (e.g., twitching or tremors)

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Specifically, 9-cis-retinol demonstrated an anti-proliferative effect, likely attributed to its conversion into 9-cis-RA (Ruiz et al., 2011)

This is especially helpful when seasonal dryness and slower cell turnover make skin feel dull or congested

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