Waist-to-hip ratio refines the waist circumference measurement by accounting for body frame size
While it intends to achieve similar goals to other dual inhibitors (enhancing glycemic control and weight loss in T2D patients), further studies may elucidate more of the unique benefits and adverse events associated with this and other dual inhibitors
AT1R antagonists inhibit sodium reabsorption in the proximal tubule leading to natriuresis via activation of unblocked angiotensin II type 2 receptors by angiotensin III [17]
In contrast, Ex-4 is only found in the venom of the lizard Heloderma suspectum , with the endogenous GLP-1 being DDP-4 sensitive and 84% identical at the amino acids level to human GLP-1 14,15
[DOI] [PubMed] [Google Scholar] [153].Blonde L, Jendle J, Gross J, Woo V, Jiang H, Fahrbach JL, Milicevic Z, Once-weekly dulaglutide versus bedtime insulin glargine, both in combination with prandial insulin lispro, in patients with type 2 diabetes (AWARD-4): a randomised, open-label, phase 3, non-inferiority study, Lancet, 385 (2015) 20572066
