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These advances could lead to novel therapeutics to target specific microbiotagutbrain signaling pathways that regulate energy and glucose homeostasis

However, because it can also remove essential minerals, proper monitoring and nutritional support are important to minimize risks

2 A separate 2-week RCT testing three GlyNAC dose levels in 114 healthy older adults found good tolerability but no significant improvement in the primary endpoint (GSH:GSSG ratio) in the full study population, highlighting that responses may depend on baseline oxidative stress levels and study duration

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