The referenced comparison trial included a daily 500-calorie deficit, 150 minutes of weekly exercise, and in-person counseling every four weeks - a fundamentally different protocol with different study populations, different variables, and different timeframes
Category 2 of the Bulk Substances Nominated Under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act Park MG, Yeo JK, Park SG, Na W, Moon DG
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Cold sensations during treatment are most likely linked to rapid weight loss and reduced caloric intake, both of which affect the body's ability to retain and generate heat