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GST overexpression and polymorphisms are seen in several cancers as well as other diseases, and have been implicated in resistance to chemotherapy 2,3

Pilot clinical studies and case reports describe nausea in 65% of subjects at doses above 0,5 mg (resolution 2-4 h post-injection), flushing in 55%, transient increases in blood pressure and tachycardia in 40-60% of subjects, with peak acute effects occurring 90-120 minutes post-dose

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