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A missense GLP1R variant (rs10305492) associated with T2D and fasting glucose was used in secondary analyses

The 3-hydroxypyruvate can then be converted to glycoaldehyde via the action of glyoxylate and hydroxypyruvate reductase (encoded by the GRHPR gene)

The FDA has warned that compounded GLP-1 drugs are not FDA-approved and are not reviewed by FDA for safety, effectiveness, or quality before marketing

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