Removal of cystine from culture medium led to a time-dependent decline of intracellular total GSH (inclusive of both GSH and GSSG, hereon referred to as GSH), with over 50% reduction at 9 hour (Fig
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Oligodendrocytes may, akin to astrocytes, exploit fatty acidderived acetyl-CoA for ketone body production within the cholesterol biosynthetic pathway, either through the action of 3-hydroxy-3-methylglutaryl-CoA lyase or via the direct deacylation of acetoacetyl-CoA (Auestad et al., 1991)
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