Approximately 20% of patients with primary ovarian insufficiency (POI) have been diagnosed with other autoimmune diseases, often thyroid, adrenal, and pancreatic diseases, and approximately 10% of patients with Addisons disease develop POI ( Figure 2 2.1.3 Iatrogenic factors Chemotherapy has multiple effects on ovarian function ( 2.1.4 Metabolic factors Ovarian function is decreased in patients with galactosemia, but the mechanisms responsible for this remain unclear
doi: 10.1093/jn/134.3.489 [DOI] [PubMed] [Google Scholar] 3.Heitzer T, Schlinzig T, Krohn K, Meinertz T, Munzel T
J Plant Biol Sci 14(4):120 Gostin IN, Blidar CF (2024) Glandular trichomes and essential oils variability in species of the genus Phlomis L.: a review
therefore, mirabegron is contraindicated in patients with uncontrolled hypertension
This significantly strengthens the livers overall detoxification capacity, helping protect liver cells from liver oxidative stress induced by toxins and supporting efficient metabolic function