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69 These include the CA index (type4 Collagen 7S and AST), NAFIC score (Non-Alcoholic steatohepatitis (NASH), serum Ferritin, serum Insulin and type IV Collagen 7S), NASH diagnostics panel, G-NASH model, and ClinLipMet score

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In December 2025, the TRIUMPH-4 trial reported that retatrutide 12 mg achieved a remarkable 28.7% mean weight loss at 68 weeks in patients with obesity and knee osteoarthritis, with substantial pain relief as well ( [71] )

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