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63 They secrete proinflammatory chemokines and cytokines such as monocyte chemotactic protein 1 (MCP-1), 64 prostaglandin E2 (PGE2), 65 interleukin 1 (IL-1), 66 IL-6, 67 IL-10, 67 tumor necrosis factor (TNF) and regulated on activation normal T cell expressed and secreted (RANTES)

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Muscle is metabolically active tissue, meaning it burns calories even at rest

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FDA-approved indications Wegovy Wegovy is indicated for: Chronic weight management in people with obesity (body mass index 30 kg/m or higher) or overweight (body mass index 27 kg/m or higher) with at least one weight-related health condition such as high cholesterol levels, hypertension (high blood pressure), heart disease, and type 2 diabetes