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While these mechanisms are of high interest in metabolic and neurodegenerative research, the complete safety profile remains under investigation

El primer estudio de eficacia y seguridad con liraglu tida realizado en una cohorte de pacientes con deterioro moderado de la funcin renal (TFGe: 30-59 ml/min/m 2 ) (LIRA-RENAL) demostr que la terapia con este AR-GLP1 se asoci a una reduccin significativamente mayor de la glucemia en ayunas con menor riesgo de hipoglucemia y sin consecuencias negativas en la funcin renal 34

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Association of chronic fatigue syndrome with human leucocyte antigen class II alleles