Kidney function tests: your eGFR and creatinine levels should be checked every 3-4 months initially, rather than the usual 6-12 months for stable CKD Hydration status: regular assessment for signs of dehydration, particularly during the first few months when nausea is most common Blood pressure monitoring: weekly home blood pressure checks, as your medication needs may change with weight loss Electrolyte levels: sodium, potassium, and other electrolytes should be monitored more frequently, particularly if you experience significant nausea or reduced appetite Medication review: regular assessment of all your medications, as doses may need adjusting with weight loss and changing kidney function Cardiovascular risk factors: CKD increases heart disease risk, so lipid (fat) and diabetes markers need monitoring alongside kidney function Your GP should coordinate this monitoring with your kidney specialist
Research on Combined Approaches A 2025 meta-analysis of 33 randomized controlled trials, involving 12,028 participants, revealed that adding lifestyle changes to GLP-1 therapy resulted in an additional 7.13 kg (15.7 lbs) of weight loss , a reduction in waist circumference by 5.74 cm , a drop in systolic blood pressure by 3.99 mmHg , and a decrease in fasting blood glucose by 6.51 mg/dL
Traditional options like steroid injections or surgery come with significant risks or diminishing returns
Adults: Warnings Caution During Administration: Follow recommended dosage and administration method and physician's instructions for administration
Some believe it enhances MT-2 results, though this isn't proven
