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Second, it argues against a pure placebo effect, because placebo responses tend to diminish more gradually
People with heart disease, hyperthyroidism, glaucoma, or uncontrolled hypertension should not take phentermine
Subjects with diabetes longer than 10 to 15 years in duration tend to have a greater chance of -cell exhaustion and thus be less responsive to the OADs, however these are generalizations and every patient may respond differently
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