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If a patient has achieved suboptimal results with one medication, healthcare professionals would typically reassess the overall weight management strategy, including dietary adherence, physical activity levels, psychological factors, and potential barriers to success, before considering switching to an alternative medication rather than adding a second agent

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A limitation of our research was the inability to assess the effects of switching from dulaglutide to other GLP-1 receptor agonists, as they were unavailable except in fixed-ratio combinations such as insulin degludec/liraglutide and insulin glargine/ lixisenatide

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