54 The phase 3 randomised controlled Study of Retratrutide in Participants with Obesity and Cardiovascular Disease (TRIUMPH-3) seeks to determine the percentage change from baseline in body weight in patients with BMI 35 kg/m 2 and established CVD (clinical trial number NCT05882045
So the long-term picture past 2027 is unsettled
Miklasiska-Majdanik, M., Kpa, M., Wojtyczka, R
Psychosom Med 80:154159 Violante S, Ijlst L, Ruiter J, Koster J, van Lenthe H, Duran M, de Almeida IT, Wanders RJ, Houten SM, Ventura FV (2013) Substrate specificity of human carnitine acetyltransferase: implications for fatty acid and branched-chain amino acid metabolism
When initiating Wegovy , consider reducing the dose of concomitantly administered insulin secretagogues or insulin to reduce the risk of hypoglycemia