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We further showed that COL I and FN exert opposite effects on MC behavior and functions: COL I elicits a highly pigmented and proliferative, but non-motile MC state, while FN triggers a less pigmented, low proliferative and highly motile MC state

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Fluid Retention and Heart Failure with Concomitant Use of PPAR-gamma Agonists: Fluid retention, which may lead to or exacerbate heart failure, can occur with concomitant use of thiazolidinediones (TZDs) and insulin