Abstract Chronic inflammation in type 2 diabetes (T2D), characterized by constitutively activated immune cells and elevated pro-inflammatory mediators along with hyperglycaemia and increased free fatty acids and branched chain amino acid levels, significantly alters the immuno-metabolic axis
Evidence suggests that GLP-1 signaling may mediate inflammatory pathways involved in some metabolic, pulmonary and neurologic disorders
"Developing new ways to treat these patients is of the utmost importance," explained study senior author Dr
Rodgers M, Migdal AL, Rodriguez TG, Chen ZZ, Nath AK, Gerszten RE, et al
However, the current American Society of Anesthesiologists (ASA) guidelines express concerns of an increased risk of aspiration in the perioperative setting due to the well-documented delayed gastric emptying