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The SC administration across different dose groups in the FIH study out of a vial would be achieved by administering: Different volumes, such as using disposable syringes with or without SC clinical pumps Using a placebo/diluent formulation to dilute to the respectively required concentrations and then administering similar volume, such as by using a disposable syringe with or without SC clinical pumps

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No association between variants in the ACE and angiotensin II receptor 1 genes and acute mountain sickness in Nepalese pilgrims to the Janai Purnima Festival at 4380 m

A patient info leaflet advises women to tell clinicians if pregnant, but also notes supplementing prevents deficiency risks