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Some patients report a brief second wave of mild headaches when their dose increases, but this recurrence is typically shorter and less intense than the initial episode

These facilities are required to follow strict safety and quality control protocols

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[57] Addition of 400,000 IU/week vitamin A to a conventional chemotherapy regimen (doxorubicin, bleomycin, 5-fluorouracil, and methotrexate) led to improved survival with less than the expected severity of side effects compared with historical controls