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GHK-Cu: A naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) with broad regenerative activity
This observation in turn emphasises the importance that therapies aimed at modulating astrocyte reactivity will need to modulate specific molecules and specific aspects of reactivity in a disorder and context specific manner
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Although paraquat may not be an efficient inhibitor of mitochondrial complex I, and so does not affect dopamine uptake [87,88], it does cause -synuclein aggregation in C57Bl/6 mice, and alters Parkin solubility, decreasing proteasome activity and causing cellular damage [87]
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