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Enhanced antitumor activity of vitamin C via p53 in cancer cells

Emerging evidence also indicates that autophagy plays a critical role in several organs, particularly in highly metabolic organs, and that its alteration is involved in the pathogenesis of metabolic disease, immunity and autoimmunity, inflammation, development, aging and cancer (19,20)

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172 (5) Improving preclinical models Existing chemically induced IBD models have notable limitations and do not fully replicate human disease mechanisms