the importance of glutathione in human disease Is Master Antioxidant? Here’s What Science Says Glutathione-Mediated Conjugation of Anticancer Drugs:

2014 Dec;101:2-30

To scientists, glutathione is known as the master antioxidant because it not only neutralizes free-radicals, it also re-activates other antioxidants like vitamins C and E, providing broad-spectrum protection for the mind and body

Direct glutathione supplementation provides the finished antioxidant, while NAC provides cysteine, the rate-limiting amino acid for your bodys own glutathione production

Modulation of TLR pathways, through agonists to boost antimicrobial defense or antagonists to dampen excessive inflammation, has emerged as a therapeutic strategy

Thus, DEM, BSO, TBH, TNF and HGF treatment of rat hepatocytes and thioacetamide treatment of rats increased the expression of GS to a comparable level as previously observed with GCL subunits (Huang et al., 2000b