Patients who monitor only weight and ignore blood sugar, blood pressure, lipid levels, and inflammatory markers miss important signals about when to continue, taper, or adjust treatment
In addition, GLP-1R agonists have been observed to enhance the health of endothelial cells in the brain, promoting vascular remodeling, which may further support cognitive function
In addition, evidence from recent experimental studies suggests that most GLP-1 analogues can be injected peripherally and absorbed into the brain, indicating that they could cross the blood-brain barrier (BBB) and exert physiological influences directly on the human brain (72) (detail seen Box 2 )
New England Journal of Medicine 2023;389:2221-32
Check with your doctor or pharmacist to be certain