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Neutrophil and Phagocytic Dysfunction Neutrophil chemotaxis, phagocytic capacity, and oxidative burst precision are all significantly impaired in Type 2 Diabetes

A recent study including spontaneously hypertensive rats and controls (WKY) reported that UA therapy (16 mg/kg) induced Kruppel-like factor 2 (KLF2) expression, lowered vascular endothelial growth factor (VEGF)-A levels, reduced BBB leakage, and improved endothelial cell barrier integrity [194, 196]

Additionally, vitamin C protects the skin from damage caused by UV rays and environmental pollutants

However, the options suggested are also problematic

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