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Changhan Lee, noted that after MOTS-c therapy, the older mice were the human equivalent of 65+, and once treated, they doubled their running capacity They were even able to outrun their middle-aged, untreated cohorts. This kind of result suggests that MOTS-c could help address age-related frailty and muscle decline

Patients with refractory epilepsy who had inflammatory conditions and those who took antioxidants as supplements or used medication were also excluded from the study