[5] In this multinational, non-randomized, open-label trial, investigators first gave a single 0.3-mg subcutaneous dose to people with Child-Pugh class A, B, or C cirrhosis and to matched healthy individuals, measuring pharmacokinetics
Data for men and women of all ages with asymptomatic iron deficiency anemia (mean age 63.7 years old) Premenopausal women included but those with HMB excluded Found a culprit lesion in 89% of patients, 13% had cancer If no culprit lesion is found, can consider video capsule endoscopy (detection rate: 35 to 77%)
Epidemiology of overdose Paracetamol poisoning is an important clinical entity as it accounts for 50% of poisonings in the UK and 10% in the USA [4, 5]
Targeting -cell production of GLP-1, specifically, in T2DM therapeutics is an idea that is being explored
TLDR: we will be watching this space and reporting as we go