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Since CSF entry correlated with plasma concentration and plasma half-life, [4] a route that lowers the plasma peak should lower central exposure further still

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A key challenge with glutathione supplements is their bioavailability, or how much gets absorbed into the bloodstream

doi: 10.1016/j.mce.2006.10.010 256 MaxelTSmidtKLarsenABennetzenMCullbergKFjeldborgKet al

A cutoff value of 10.2 nmol/mg for GSH was identified, and the area under the ROC curve was 0.913, with a sensitivity of 90.2% and a specificity of 81.8%, demonstrating significant predictive capability in differentiating between the resistant group and sensitive group