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NSAIDs are a common cause of gastric ulcers and intestinal lesions due to their inhibition of prostaglandin synthesis, which is crucial for mucosal defense

Specifically, it produces no IGF-1 elevation (avoiding proliferative concerns), no negative impact on glucose metabolism (avoiding diabetes risk), no fluid retention or edema, and no concerning patterns of joint pain that can occur with growth hormone

International longevity expert Luigi Fontana from the University of Sydney told Four Corners there was no human clinical trial evidence that NAD+ had health or anti-aging benefits, nor was he aware of any safety data

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