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Caloric Restriction Mimicry: Mimics metabolic effects of caloric restriction, including reduced mTOR signaling, enhanced autophagy, and improved metabolic flexibility (10)

Obesity : Excess body weight is associated with metabolic changes that increase urinary excretion of calcium, oxalate, and uric acid, all of which contribute to stone formation

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Previous studies have elucidated the role of melatonin in improving animal reproductive performance, and this factor can potentially improve human-assisted reproduction in the future

Mice were treated every other day for a total of ten doses, with daily body weight and food intake measurements (schematic of study design Fig