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Clinical Investigation of LY3437943

People with CKD have reduced reserves for handling fluid loss, making slow dose escalation and consistent hydration critical

This work was supported by grants from the Hainan Province Clinical Medical Center (QWYH202175), the Scientific Research Project of Hainan Health Committee (21A200115), the Research and Cultivation Fund of Hainan Medical University (HYPY2020015), the Specific Research Fund of The Innovation Platform for Academicians of Hainan Province (YSPTZX202311), the Natural Science Foundation of Hainan Province (820RC771), and the Key R&D Projects of Hainan Province (ZDYF2022SHFZ074)

Bone turnover marker dynamics VSG induces a consistent activation of bone turnover across age groups, characterized by elevations in both resorption and formation markers

As a GLP-1 receptor agonist, it mimics the hormone that regulates appetite and insulin, making weight loss easier by reducing hunger and stabilizing blood sugar