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Aidah Abu El Soud Alkaissi An-Najah National University Faculty of Nursing Paracetamol intoxicationAcetaminophen (N-acetyl-p-aminophenol) Acetaminophen is primarily biotransformed to nontoxic products in the liver via conjugation with glucuronic acid and, to a lesser degree, sulfate, and eliminated by the kidneys A small proportion (5-15%) of acetaminophen is metabolized through the cytochrome P-450 enzyme pathway producing a highly reactive and toxic metabolite, N-acetyl-para-benzoquinoneimine (NAPQI) which may cause hepatic injury Dr

A brain and nervous system (neurologic) examination helps confirm leg weakness and loss of sensation in the legs

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