That extended activity window changes everything about how the peptide works in the body
Some are more closely tied to cardiac health, some to metabolism and some to neurological health
Around 10% to 20% of patients may suffer from temporary and manageable side effects, including lethargy, inappetence, diarrhoea, nausea and vomiting
Brit J Anaesthesia
Dietary influences are the most common cause of stool colour variation: Green stools : leafy vegetables (spinach, kale), green food colouring Red or reddish stools : beetroot, tomatoes, red food dyes, cranberries Orange stools : foods high in beta-carotene (carrots, sweet potatoes), rifampicin (an antibiotic) Dark brown to black : iron supplements, bismuth subsalicylate, liquorice, blueberries Pale or light-coloured : primarily caused by reduced bile flow into the intestine Medications and supplements frequently alter stool appearance: Iron supplements commonly cause dark green or black stools Rifampicin and rifabutin can produce orange-red discolouration Bismuth subsalicylate causes black stools Some vitamins and herbal supplements contain pigments that pass through the digestive system Medical conditions that may affect stool colour include: Pale/clay-coloured : biliary obstruction, hepatitis, cirrhosis, pancreatic disorders Black/tarry : upper gastrointestinal bleeding (peptic ulcers, gastritis) Bright red : lower gastrointestinal bleeding (haemorrhoids, diverticular disease, colorectal pathology) Yellow/greasy : malabsorption syndromes, coeliac disease, chronic pancreatitis Green : rapid intestinal transit, certain infections Patients commencing GLP-1 therapy often simultaneously modify their diet significantly, increasing vegetable intake and reducing processed foods as part of weight management efforts
