GSH Nebraska: general info + transporters Comprehensive reviews The Incomplete Glutathione Puzzle: Just Guessing at Numbers and Figures?2017 Tissue distribution and concentration 2-5 mM according to the tissue (5 mM = 1,5366 mg/ml) half-life GSH half life It ranges from 3/5 hours to 30/50 hours If we assume 40kg tissues with an average 2.5 mM GSH (ca 750 mg/l) it means 30 g GSH in the whole body with an half-life of 48hours its life is around 10 days
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Supplementing orally with raw cysteine, or whole glutathione for that matter, is not practical because it would be destroyed in the digestion process before reaching the cell
Weeks 9 through 12: 1 mg once weekly (if tolerated and weight loss is insufficient at 0.5 mg)