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Mistake 1: inadequate duration Many users expect immediate results and give up after 2-3 weeks of minimal change

After completing the phase 3 efficacy trial in August 2025, Moderna reported that it held a presubmission meeting with CBER and received written feedback requesting additional supportive analyses on the comparator and noted this would be a significant issue during BLA review

Patients with strong genetic signals for GLP-1 responsiveness often achieve better sustained results, helping guide whether long-term therapy is likely to work well for your biology