retatrutide mechanism triple agonist gip glp-1 glucagon Triple Agonism Based Therapies for

doi: 10.1002/jnr.24090 3 HaghikiaAHohlfeldRGoldRFuggerL

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any new palpitations should be assessed promptly by a clinician [5] [9] Severe or persistent upper abdominal pain, particularly if it radiates to the back and is accompanied by vomiting this may indicate pancreatitis or a gallbladder problem and requires prompt medical review Severe or worsening nausea, vomiting, or diarrhoea that is preventing adequate nutrition or hydration, as this may lead to dehydration and, in some cases, acute kidney injury

PMID 31643176

4.2 Astrocyte S100B and glial fibrillary acidic protein (GFAP) are prominent astrocyte biomarkers