There are some theoretical risks to consider: Uncontrolled tissue growth, including fibrotic scar tissue Nerve ingrowth, which can contribute to chronic pain in tendons Potential tumour stimulation, given its role in promoting blood vessel formation In short, we dont yet know how it behaves in the human body over time, or how it might interact with other medications or health conditions
Indian J Biochem Biophys
The peptide undergoes rapid first-pass metabolism when absorbed, which is why bioavailability varies significantly by administration route
The future potential to enable testing in different settings outside of hospital clinics is hugely exciting. Beyond Alzheimers, the technique could support research into Parkinsons disease, multiple sclerosis, ALS and brain injuries, thanks to its ability to measure NfL
These interventions have strong evidence, predictable outcomes, and clear safety profiles for knee patients