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If you want more context on timing and how dose frequency differs across GLP-1s, this guide to GLP-1 half-life is a helpful companion read

GLP-1 also signals to the brain to reduce appetite and slow down the rate of food digestion, which can lead to weight loss

The heaviest participants, followed out to two years, lost 30.3 percent, around 85 pounds

Patients who commit to and maintain lifestyle changes in diet and exercise are more likely to keep a substantial amount of the weight off after discontinuing GLP-1 medications

Healthy habits make a difference : Building consistent routines around movement, nutrition, sleep, and stress management can help preserve your progress after stopping a GLP-1