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A third widely-cited paper (McCoy 2013, PMID 23055539) the source of the often-repeated "seven orders of magnitude more potent than BDNF" line carries a 2021 Expression of Concern

These compounds come primarily from two sources: the food you eat and the bile your liver produces to help digest fats

USA 108 , 84088413 (2011)

Mitochondrial dysfunction as a common hub Mitochondria, often called the "powerhouses of the cell", are key integrators of metabolic, oxidative, and signaling pathways vital for the proper functioning of cardiac and neural tissues