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doi: 10.1002/glia.20467 176 QiuX.WuG.WangL.TanY.SongZ

Blocks NNMT in fat cells In 3T3-L1 mouse fat cells, 30 M of 5-Amino-1MQ for 24 hours strongly lowered 1-MNA levels direct proof of NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

found that caloric restriction increased Treg cells, altered the metabolic state of immune cells, and downregulated glycolysis-related genes by single-cell RNA sequencing

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